Choosing Alzheimers disease prevention clinical trial populations.

 
   Lead Investigator:    Joshua Grill
   Institution      :    UCLA
   E-Mail           :    jgrill@mednet.ucla.edu
   Proposal ID      :    262


   Publications:


1  Grill JD,  Monsell S
   Choosing Alzheimer's disease prevention trial populations
   Abstract  J Nutr Health Aging,17:815-816,2013,

   PUBLISHED



2  Grill JD,  Monsell S
   Choosing Alzheimer's disease prevention clinical trial populations
   Journal Article  Neurobiol Aging,35:466-471,2014,PMC3864603

   PUBLISHED





   Proposal Description:
   Aim 1: To examine the proportion of UDS subjects eligible for AD prevention trials with varying age. Aim 2: To determine what criteria most frequently exclude potential participants and whether this changes with age. Aim 3: To examine changes over time in cognitive outcome measures for trial eligible populations and compare the implications of age cut-offs and outcome choices in the setting of an AD prevention trial.